Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379724 | 1.00 | MGLL (0.38) | MGLLFAAHTRPV1CES1TNNC1 | |
| SCHEMBL31554340 | 1.00 | MGLL (0.38) | MGLLFAAHTRPV1CES1TNNC1 | |
| SCHEMBL31681667 | 0.93 | PDE5A (0.31) | MGLL | |
| SCHEMBL10795323 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL11205811 | 0.74 | TAAR1 (0.32) | — | |
| SCHEMBL4618358 | 0.73 | MGLL (0.41) | MGLLFAAHTRPV1 | |
| SCHEMBL4618548 | 0.73 | MGLL (0.41) | MGLLFAAHTRPV1 | |
| SCHEMBL7529684 | 0.71 | NPC1 (0.50) | FAAHCES1 | |
| SCHEMBL3115987 | 0.71 | NPC1 (0.50) | FAAHCES1 | |
| SCHEMBL4619602 | 0.71 | MGLL (0.39) | MGLLFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |