SCHEMBL4379749

SCHEMBL4379749

COc1cc2c(=O)[nH]cnc2cc1OCCCN1CCSCC1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 15/20 0.50
EHMT1 Q9H9B1 14/20 0.50
KDR P35968 1/20 0.46
SPIN1 Q9Y657 2/20 0.45
MET P08581 1/20 0.44
KDM1A O60341 1/20 0.44
DNMT1 P26358 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211058 0.95 PDGFRB (0.47) EHMT2EHMT1KDRMET
SCHEMBL4686452 0.90 EHMT2 (0.61) EHMT2EHMT1KDRSPIN1
SCHEMBL2924579 0.89 EHMT2 (0.60) EHMT2EHMT1KDRSPIN1
SCHEMBL4025116 0.89 EHMT2 (0.52) EHMT2EHMT1KDRMETDNMT1
SCHEMBL829762 0.87 KDM1A (0.57) KDRMETKDM1A
SCHEMBL1734721 0.87 KDM1A (0.57) KDRMETKDM1A
SCHEMBL29478513 0.87 KDM1A (0.57) KDRMETKDM1A
SCHEMBL29478512 0.87 KDM1A (0.57) KDRMETKDM1A
Hydrochloric Acid SCHEMBL4378504 0.86 KDM1A (0.56) KDRMETKDM1A
Hydrochloric Acid SCHEMBL27988356 0.86 KDM1A (0.56) KDRMETKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050080262-A1 Process for producing quinazolin-4-one derivative UBE INDUSTRIES, LTD. (JP) 2005-04-14 US claimed
EP-1477481-A1 PROCESS FOR PRODUCING QUINAZOLIN-4-ONE DERIVATIVE Ube Industries, Ltd. (JP) 2004-11-17 EP claimed
US-8367824-B2 Reacting anthranilic acid with formic acid compound in presence of a catalyst and solvent UBE INDUSTRIES LTD. (JP) 2013-02-05 US disclosed
EP-1477481-B1 PROCESS FOR PRODUCING QUINAZOLIN-4-ONE DERIVATIVE UBE INDUSTRIES (JP) 2009-07-22 EP disclosed
US-20050080262-A1 Process for producing quinazolin-4-one derivative UBE INDUSTRIES, LTD. (JP) 2005-04-14 US disclosed
EP-1477481-A1 PROCESS FOR PRODUCING QUINAZOLIN-4-ONE DERIVATIVE Ube Industries, Ltd. (JP) 2004-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080262-A1 Process for producing quinazolin-4-one derivative NQO2, SDHA, CYP3A4 EHMT2 2872/4885EHMT1 2444/4885KDR 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.