SCHEMBL4380206

SCHEMBL4380206

C=C(/C=C(\OC)O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2169763 1.00
SCHEMBL2169769 1.00
SCHEMBL9510313 0.93
SCHEMBL13982681 0.91
SCHEMBL9506608 0.91
SCHEMBL9506606 0.91
SCHEMBL20089272 0.77
SCHEMBL13588926 0.77
SCHEMBL1841927 0.77
SCHEMBL17866585 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282743-A1 METHODS OF SYNTHESIZING CANNABIDIOL, DERIVATIVES THEREOF, AND OTHER PHYTOCANNABINOIDS CITRACHEM CORP. 2025-09-11 US disclosed
US-9701642-B2 Method for producing optically active 5-hydroxy-3-ketoester NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-07-11 US disclosed
US-20160185734-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 5-HYDROXY-3-KETOESTER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-06-30 US disclosed
EP-1472227-B1 PROCESS FOR THE MANUFACTURE OF ORGANIC COMPOUNDS NOVARTIS AG (CH) 2016-04-27 EP disclosed
US-8188306-B2 Heat shock protein 90 inhibitors UNIVERSITY OF KANSAS (US) 2012-05-29 US disclosed
US-8188306-B2 Heat shock protein 90 inhibitors UNIVERSITY OF KANSAS (US) 2012-05-29 US disclosed
US-20100099865-A1 HEAT SHOCK PROTEIN 90 INHIBITORS UNIVERSITY OF KANSAS (US) 2010-04-22 US disclosed
US-20100099865-A1 HEAT SHOCK PROTEIN 90 INHIBITORS UNIVERSITY OF KANSAS (US) 2010-04-22 US disclosed
EP-1493744-B1 Tropane analogs and methods for inhibition of monoamine transport ORGANIX INC (US) 2009-11-25 EP disclosed
US-7605288-B2 Heat shock protein 90 inhibitors UNIVERSITY OF KANSAS (US) 2009-10-20 US disclosed
WO-1999002526-A1 TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT ORGANIX, INC. (US) 1999-01-21 WO disclosed
US-5770180-A COCAINE ORGANIX, INC. (US) 1998-06-23 US disclosed
WO-1997040859-A1 BRIDGE-SUBSTITUTED TROPANES AND USES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1997-11-06 WO disclosed
US-5506359-A TROPANE COMPOUNDS USEFUL FOR IMAGING AND TREATING PARKINSON'S DISEASE AND COCAINE ABUSE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1996-04-09 US disclosed
WO-1994004146-A1 COCAINE ANALOGUES AND THEIR USE AS COCAINE DRUG THERAPIES AND THERAPEUTIC AND IMAGING AGENTS FOR NEURODEGENERATIVE DISORDERS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-03-03 WO disclosed
EP-0271829-B1 DELTA-HYDROXY-BETA-LYSINE DERIVATIVES AND THEIR PRODUCTION Takeda Chemical Industries, Ltd. (JP) 1993-08-25 EP disclosed
US-5120848-A Anticholesterol and antilipemic agents; hydroxy-3-methylglutaryl/3-/ coenzyme A reductase inhibitors GLAXO GROUP LIMITED (GB) 1992-06-09 US disclosed
US-5013749-A Imidazole derivatives and their use as hypercholesterolemia and hyperlipoproteinemia agents GLAXO GROUP LIMITED (GB) 1991-05-07 US disclosed
US-4906659-A Antibiotic tan-749, its derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-03-06 US disclosed
EP-0271829-A2 Delta-hydroxy-beta-lysine derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1988-06-22 EP disclosed