Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388100 | 0.84 | GSK3B (0.34) | PTGER1RXRARXRBRXRGPTGER4 | |
| SCHEMBL4381514 | 0.74 | CA9 (0.40) | PTGER1PTGER4PTGER3PTGER2CYP2C9 | |
| SCHEMBL4381082 | 0.72 | CA9 (0.40) | PTGER1RXRARXRBRXRGPTGER4 | |
| SCHEMBL4380949 | 0.72 | PTGER1 (0.46) | PTGER1CYP2C9KMT2AMRGPRX4 | |
| SCHEMBL4379396 | 0.72 | PTGER1 (0.46) | PTGER1CYP2C9KMT2AMRGPRX4 | |
| SCHEMBL4381387 | 0.71 | MAPK14 (0.35) | PTGER1PTGER4PTGER3PTGER2MCL1 | |
| SCHEMBL4381854 | 0.71 | CDK5 (0.36) | TDP1 | |
| SCHEMBL4385084 | 0.71 | MAPK14 (0.35) | PTGER1PTGER4PTGER3PTGER2MCL1 | |
| SCHEMBL4384038 | 0.71 | MAPK14 (0.35) | PTGER1PTGER4PTGER3PTGER2MCL1 | |
| SCHEMBL4378114 | 0.70 | KDM4E (0.39) | PTGER1CYP2C9MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | PTGER1 3751/4885RXRA 1665/4885RXRB 1596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.