Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 19/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056241 | 0.87 | CA1 (0.39) | CA1CA2TBXAS1 | |
| SCHEMBL4847585 | 0.82 | CA1 (0.41) | CA1CA2TBXAS1 | |
| SCHEMBL14314683 | 0.73 | CA1 (0.55) | CA1CA2TBXAS1 | |
| SCHEMBL4848914 | 0.73 | CA1 (0.44) | CA1CA2TBXAS1 | |
| SCHEMBL14135218 | 0.72 | CA1 (0.54) | CA1CA2TBXAS1 | |
| SCHEMBL18843235 | 0.72 | CA1 (0.59) | CA1CA2TBXAS1 | |
| SCHEMBL13764949 | 0.72 | CA1 (0.59) | CA1CA2TBXAS1 | |
| SCHEMBL3553296 | 0.72 | CA1 (0.59) | CA1CA2TBXAS1 | |
| SCHEMBL4845250 | 0.69 | CA1 (0.41) | CA1CA2TBXAS1 | |
| SCHEMBL13547264 | 0.67 | CA1 (0.60) | CA1CA2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765073-A4 | ANALOGS OF DICTYOSTATIN, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | UNIV PITTSBURGH (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-1765073-A2 | ANALOGS OF DICTYOSTATIN, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005117588-A2 | ANALOGS OF DICTYOSTATIN, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2005-12-15 | — | — | WO | disclosed |