SCHEMBL4380669

SCHEMBL4380669

O=C(O)c1c(CC(Br)CBr)c(CC(Br)CBr)c(C(=O)O)c(C(=O)O)c1CC(Br)CBr

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11786175 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4808029 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL6690566 0.76 PTPN1 (0.33) TSHR
SCHEMBL94558 0.73 CYP1A2 (0.39) ALDH1A1TSHR
SCHEMBL96057 0.72 CYP1A2 (0.31)
SCHEMBL29504085 0.71 PTGS1 (0.44) TSHR
SCHEMBL14989209 0.71 PTGS1 (0.44) TSHR
SCHEMBL6690570 0.70
SCHEMBL16965873 0.68 POLB (0.33)
SCHEMBL14989194 0.66 PTGS1 (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US claimed
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US disclosed
EP-1889869-B1 Flame-retarded foamed plastic compositions and shaped articles DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2009-11-25 EP disclosed
EP-1889869-A1 Flame-retarded foamed plastic compositions and shaped articles Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2008-02-20 EP disclosed
EP-1712586-A1 Flame-retarded foamed plastic compositions and shaped articles Dai-Ichi F R Co., Ltd. (JP) 2006-10-18 EP disclosed
US-20060229372-A1 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-12 US disclosed
US-4125733-A SOIL RELEASE, FIREPROOFING PENNWALT CORPORATION (US) 1978-11-14 US disclosed