Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8308431 | 1.00 | — | — | |
| Acetic Acid SCHEMBL4772902 | 0.97 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TP53 | |
| Acetic Acid SCHEMBL582893 | 0.97 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TP53 | |
| Bicarbonate SCHEMBL9202821 | 0.90 | — | — | |
| Methacrylic Acid SCHEMBL28334060 | 0.86 | ALDH1A1 (0.36) | FFAR3LCKFYNALDH1A1TP53 | |
| Acetic Acid SCHEMBL11120881 | 0.84 | — | — | |
| Acetic Acid SCHEMBL28925246 | 0.84 | — | — | |
| SCHEMBL54589 | 0.83 | — | — | |
| SCHEMBL3161530 | 0.83 | — | — | |
| SCHEMBL41930 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180175468-A1 | COOLING PLATE FOR WEIGHT LIGHTENING, BATTERY MODULE COMPRISING THE SAME AND METHOD FOR MANUFACTURING THE SAME | LG CHEM, LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| EP-2618215-B1 | Method for producing a lithographic printing plate | FUJIFILM CORP (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-1602982-B1 | Planographic printing method | FUJIFILM CORP (JP) | 2013-12-18 | — | — | EP | disclosed |
| EP-2618215-A1 | Method for producing a lithographic printing plate | Fujifilm Corporation (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20090293748-A1 | PLATEMAKING METHOD FOR LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLANOGRAPHIC PRINTING METHOD | MITSUMOTO TOMOYOSHI | 2009-12-03 | — | — | US | disclosed |
| EP-1602982-A2 | method of producing a lithographic printing plate and planographic printing method | FUJI PHOTO FILM CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20050263021-A1 | Platemaking method for lithographic printing plate precursor and planographic printing method | FUJI PHOTO FILM CO., LTD. | 2005-12-01 | — | — | US | disclosed |