Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168704 | 0.86 | GPR3 (0.40) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4381332 | 0.86 | POLB (0.42) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13186074 | 0.81 | GPR3 (0.38) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1408375 | 0.72 | SMN1; SMN2 (0.56) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL17394563 | 0.71 | GPR3 (0.50) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13212785 | 0.68 | CYP1A2 (0.52) | GPR3POLBCYP1A2CYP2C19KDM4E | |
| SCHEMBL1906715 | 0.68 | POLB (0.55) | GPR3POLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12150652 | 0.67 | GPR3 (0.46) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL19583449 | 0.67 | GPR3 (0.46) | GPR3POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8804817 | 0.66 | TSHR (0.50) | POLBSMN1; SMN2CYP1A2NPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629379-B2 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2009-12-08 | — | — | US | disclosed |
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2007-03-01 | — | — | US | disclosed |
| EP-1625134-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101579-A2 | SUBSTITUTED PHOSPHONATE FLUORESCENT SENSORS AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | NR2E3, CASR, NR3C2 | GPR3 48/4885POLB 2167/4885SMN1; SMN2 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.