Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.71 |
| ▸ | AKT2 | P31751 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065667 | 0.93 | PIM1 (0.67) | PIM1AKT2HTTKDRMEN1 | |
| SCHEMBL810522 | 0.93 | PIM1 (0.77) | PIM1AKT2HTTKDRMEN1 | |
| SCHEMBL5065555 | 0.91 | PIM1 (0.70) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL5067844 | 0.87 | PIM1 (0.55) | PIM1AKT2HTTKDRMAOA | |
| SCHEMBL5061334 | 0.87 | PIM1 (0.66) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810678 | 0.86 | PIM1 (0.71) | PIM1AKT2HTTKDRMEN1 | |
| SCHEMBL810188 | 0.86 | PIM1 (0.73) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810579 | 0.85 | PIM1 (0.76) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810708 | 0.85 | PIM1 (0.69) | PIM1AKT2HTTKDREGFR | |
| SCHEMBL810332 | 0.85 | PIM1 (0.72) | PIM1AKT2KDRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094276-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008133753-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2008-11-06 | — | — | WO | disclosed |
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |