Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.67 |
| ▸ | AKT2 | P31751 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810678 | 0.93 | PIM1 (0.71) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL4381544 | 0.93 | PIM1 (0.71) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL5061334 | 0.92 | PIM1 (0.66) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL5061756 | 0.90 | PIM1 (0.54) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL5065555 | 0.87 | PIM1 (0.70) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL5068961 | 0.87 | PIM1 (0.52) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810188 | 0.86 | PIM1 (0.73) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL809927 | 0.86 | PIM1 (0.71) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810332 | 0.86 | PIM1 (0.72) | PIM1AKT2KDRMEN1MAPT | |
| SCHEMBL810522 | 0.85 | PIM1 (0.77) | PIM1AKT2KDRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |