Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4374293 | 0.99 | MAPK14 (0.64) | MAPK14MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL6504887 | 0.88 | MAPK14 (0.77) | MAPK14 | |
| SCHEMBL13603242 | 0.86 | MAPK14 (0.67) | MAPK14MAPKAPK2 | |
| SCHEMBL29594257 | 0.86 | MAPK14 (0.66) | MAPK14MAPKAPK2 | |
| SCHEMBL5862529 | 0.86 | MAPK14 (0.66) | MAPK14MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL30335930 | 0.86 | MAPK14 (0.66) | MAPK14MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL4377540 | 0.86 | MAPK14 (0.66) | MAPK14MAPKAPK2 | |
| SCHEMBL5862997 | 0.85 | MAPK14 (0.62) | MAPK14MAPKAPK2 | |
| SCHEMBL31080077 | 0.85 | MAPK14 (0.59) | MAPK14MAPKAPK2 | |
| SCHEMBL5861958 | 0.85 | MAPK14 (0.59) | MAPK14MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | claimed |
| CN-114748622-A | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | 弗尔康医疗公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114732910-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111601593-B | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-111601593-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2020-08-28 | — | — | CN | disclosed |
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |