Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.50 |
| ▸ | DRD2 | P14416 | 17/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385465 | 0.88 | DRD3 (0.42) | DRD3KCNH2DRD2 | |
| SCHEMBL4384802 | 0.81 | DRD3 (0.54) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| SCHEMBL4386866 | 0.81 | DRD3 (0.55) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| SCHEMBL4395457 | 0.80 | DRD3 (0.52) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| Hydrochloric Acid SCHEMBL7202732 | 0.80 | DRD3 (0.64) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| SCHEMBL4562741 | 0.79 | DRD3 (0.53) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| SCHEMBL4703079 | 0.77 | DRD3 (0.59) | DRD3KCNH2DRD2 | |
| SCHEMBL4702317 | 0.77 | DRD3 (0.56) | DRD3KCNH2DRD2CYP3A4CHRM1 | |
| SCHEMBL4387200 | 0.77 | DRD3 (0.58) | DRD3KCNH2DRD2 | |
| SCHEMBL4390866 | 0.75 | DRD3 (0.56) | DRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144405-B1 | TRIAZOLE COMPOUNDS WITH DOPAMINE-D3-RECEPTOR AFFINITY | ABBOTT GMBH & CO KG (DE) | 2009-11-25 | — | — | EP | disclosed |
| US-6602867-B1 | Triazole compounds with dopamine-D3-receptor affinity | ABBOTT LABORATORIES | 2003-08-05 | — | — | US | disclosed |