Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431195 | 0.98 | CA1 (0.45) | CA1CA2CA7CTSKITGB3 | |
| SCHEMBL25320849 | 0.95 | CA1 (0.47) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL25320847 | 0.95 | CA1 (0.47) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL86237 | 0.88 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL86310 | 0.88 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1654201 | 0.88 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL24248045 | 0.85 | CAPN1 (0.48) | CA1CA2CA7ITGB3ITGA2B | |
| SCHEMBL24465592 | 0.85 | CTSK (0.56) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL28398590 | 0.85 | CTSK (0.56) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL24739376 | 0.85 | CTSK (0.56) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140467-A1 | OXOBENZINDOLIZINOQUINOLINES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2009-11-19 | — | — | WO | disclosed |
| EP-1306372-A1 | HETEROCYCLE DERIVATIVES AND DRUGS | Nippon Shinyaku Co., Ltd. (JP) | 2003-05-02 | — | — | EP | disclosed |