Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371354 | 0.94 | CNR2 (0.44) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4374299 | 0.92 | CNR2 (0.42) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4376908 | 0.91 | CNR2 (0.39) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4379995 | 0.86 | CNR2 (0.39) | CNR2TSHR | |
| SCHEMBL4375460 | 0.85 | TSHR (0.40) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4374742 | 0.85 | TSHR (0.42) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4376045 | 0.85 | TSHR (0.42) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4382724 | 0.84 | TSHR (0.39) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4369418 | 0.84 | TSHR (0.38) | CNR2TSHRKDM4EALDH1A1GLA | |
| SCHEMBL4380548 | 0.84 | TSHR (0.38) | CNR2TSHRKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |