Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380421 | 0.92 | CNR2 (0.39) | CNR2TSHRKMT2AGRIN1GRIN2B | |
| SCHEMBL4382397 | 0.86 | CNR2 (0.42) | CNR2TSHR | |
| SCHEMBL5614389 | 0.85 | RORC (0.38) | CNR2KMT2AGRIN1GRIN2BPDK1 | |
| SCHEMBL4375462 | 0.84 | TSHR (0.39) | CNR2TSHRKMT2AGRIN1GRIN2B | |
| SCHEMBL4373433 | 0.84 | ALDH1A1 (0.40) | CNR2TSHRKMT2AGRIN1GRIN2B | |
| SCHEMBL4372670 | 0.82 | CNR1 (0.42) | CNR2TSHRKMT2AGRIN1GRIN2B | |
| SCHEMBL4373529 | 0.80 | CNR2 (0.39) | CNR2TSHRKMT2AGRIN1GRIN2B | |
| SCHEMBL4371354 | 0.80 | CNR2 (0.44) | CNR2TSHR | |
| SCHEMBL4374299 | 0.79 | CNR2 (0.42) | CNR2TSHR | |
| SCHEMBL4376908 | 0.77 | CNR2 (0.39) | CNR2TSHRKMT2AGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |