⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035007 | 0.83 | — | — | |
| SCHEMBL44357 | 0.76 | — | — | |
| SCHEMBL6284528 | 0.69 | — | — | |
| SCHEMBL284721 | 0.67 | — | — | |
| SCHEMBL20876138 | 0.65 | — | — | |
| SCHEMBL9762888 | 0.65 | — | — | |
| SCHEMBL34332 | 0.64 | — | — | |
| Sulfuric Acid SCHEMBL25385431 | 0.59 | — | — | |
| Sulfuric Acid SCHEMBL21225969 | 0.59 | — | — | |
| Sulfuric Acid SCHEMBL21225968 | 0.59 | CA5A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101636417-A | Low molecular weight heparins comprising at least one covalent bond with biotin or a biotin derivative, their manufacture and their use | SANOFI AVENTIS | 2010-01-27 | — | — | CN | disclosed |
| CN-101605549-A | Heparin comprising at least one covalent bond with biotin or a biotin derivative, its preparation and use | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | CN | disclosed |
| EP-2121769-A1 | LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | disclosed |
| EP-2120970-A1 | HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR PREPARING SAME AND USE THEREOF | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008113918-A1 | HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR PREPARING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008113919-A1 | LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2008-09-25 | — | — | WO | disclosed |