SCHEMBL438314

SCHEMBL438314

CCOC(=O)C(=Cc1ccc(OC)cc1)C(=O)OCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.70
KMT2A Q03164 7/20 0.70
MAPT P10636 7/20 0.69
LMNA P02545 3/20 0.69
NPSR1 Q6W5P4 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
S1PR4 O95977 1/20 0.69
S1PR1 P21453 1/20 0.69
MAPK1 P28482 1/20 0.69
NR1H4 Q96RI1 1/20 0.63
KDM4E B2RXH2 3/20 0.56
ALDH1A1 P00352 3/20 0.56
HSP90AA1 P07900 2/20 0.56
HPGD P15428 1/20 0.56
PLIN1 O60240 1/20 0.55
POLB P06746 1/20 0.55
PLIN5 Q00G26 1/20 0.55
ABHD5 Q8WTS1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14811753 0.95 MEN1 (0.64) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL8182437 0.95 MEN1 (0.64) MEN1KMT2AMAPTLMNANPSR1
Malonic Acid SCHEMBL6825036 0.93 MEN1 (0.65) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL30553780 0.92 KMT2A (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10851464 0.92 KMT2A (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL134782 0.92 MEN1 (0.64) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10851473 0.92 KMT2A (0.66) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL1068265 0.89 MEN1 (0.85) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL11776370 0.88 NR1H4 (0.55) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL11729192 0.88 MEN1 (0.55) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841982-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119841979-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119841980-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2025-04-18 CN claimed
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells NORTHEAST NORMAL UNIVERSITY (CN) 2020-07-28 US claimed
CN-106543314-B The application of catalyst containing ether ester and the catalyst and ether ester in olefin polymerization 中国石油化工股份有限公司 2019-02-19 CN claimed
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS NORTHEAST NORMAL UNIVERSITY (CN) 2018-07-12 US claimed
EP-1082015-B1 STABILIZED ANTIMICROBIAL COMPOSITIONS CONTAINING HALOPROPYNYL COMPOUNDS TROY TECHNOLOGY CORP INC (US) 2007-06-27 EP claimed
EP-1082015-A4 STABILIZED ANTIMICROBIAL COMPOSITIONS CONTAINING HALOPROPYNYL COMPOUNDS TROY TECHNOLOGY CORP INC (US) 2002-03-20 EP claimed
EP-1082015-A1 STABILIZED ANTIMICROBIAL COMPOSITIONS CONTAINING HALOPROPYNYL COMPOUNDS Troy Technology Corporation, Inc. (US) 2001-03-14 EP claimed
WO-1999059410-A1 STABILIZED ANTIMICROBIAL COMPOSITIONS CONTAINING HALOPROPYNYL COMPOUNDS TROY TECHNOLOGY CORPORATION, INC. (US) 1999-11-25 WO claimed
US-5938825-A ALSO CONTAINING SELECTED ULTRAVIOLET RADIATION ABSORBER TROY TECHNOLOGY CORPORATION INC. (US) 1999-08-17 US claimed
EP-0848947-B1 Compositions containing a derivative of dibenzoylmethane, a derivative of 1,3,4-triazine and an dialkly benyalmalonate OREAL (FR) 1999-08-11 EP claimed
US-5882634-A COSMETICS AND SKINS SOCIETE L'OREAL S.A. (FR) 1999-03-16 US claimed
US-5670140-A SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE L'OREAL (FR) 1997-09-23 US claimed
US-5624663-A Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates L'OREAL (FR) 1997-04-29 US claimed
JP-10175838-A None JP disclosed
US-12617955-B2 Additive production process with a thermoplastic radically cross-linkable construction material STRATASYS, INC. (US) 2026-05-05 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed
US-3958003-A HETEROCYCLIC COMPOUND, ANALGESICS CENTRAL NERVOUS SYSTEM DEPRESSANT SANDOZ LTD. (CH) 1976-05-18 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS XPA, MEP1A, EED MEN1 809/4885KMT2A 1689/4885MAPT 4688/4885
US-12617955-B2 Additive production process with a thermoplastic radically cross-linkable construction material UBE2G2, MTCL3, RAD51 MEN1 2540/4885KMT2A 2613/4885MAPT 253/4885
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells XPA, MEP1A, EED MEN1 809/4885KMT2A 1689/4885MAPT 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.