⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564664 | 0.78 | — | — | |
| SCHEMBL253464 | 0.71 | NPC1 (0.32) | — | |
| SCHEMBL10009873 | 0.70 | — | — | |
| SCHEMBL943487 | 0.69 | — | — | |
| SCHEMBL10774939 | 0.67 | — | — | |
| SCHEMBL5331066 | 0.65 | — | — | |
| SCHEMBL3623472 | 0.65 | — | — | |
| SCHEMBL15526324 | 0.65 | — | — | |
| SCHEMBL27438121 | 0.65 | — | — | |
| SCHEMBL1809810 | 0.64 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960741-A1 | QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Academy Of Military Medical Sciences (CN) | 2022-03-02 | — | — | EP | claimed |
| EP-2170350-B1 | SUBSTITUTED IMIDAZOHETEROCYCLES | CARA THERAPEUTICS INC (US) | 2013-09-11 | — | — | EP | claimed |
| CN-112142747-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20240018124-A1 | MODULATORS OF FPR1 AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-01-18 | — | — | US | disclosed |
| CN-116033897-A | Phenol derivatives | 住友制药株式会社 | 2023-04-28 | — | — | CN | disclosed |
| EP-3712147-B1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |
| CN-115246787-A | Meta-disubstituted compound, preparation thereof and application thereof in preventing and treating mosquito and plant pathogenic bacteria | 吉林省达凯生物医药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| WO-2022050385-A1 | PHENOL DERIVATIVE | 大日本住友製薬株式会社 | 2022-03-10 | — | — | WO | disclosed |
| EP-3960741-A1 | QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Academy Of Military Medical Sciences (CN) | 2022-03-02 | — | — | EP | disclosed |
| US-10822365-B1 | SGLTS inhibitor and application thereof | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2020-11-03 | — | — | US | disclosed |
| US-20200331950-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-10-22 | — | — | US | disclosed |
| EP-3712147-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | Shangdong Danhong Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| EP-2094081-A1 | TRICYCLIC HETEROAROMATIC COMPOUNDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | Merck & Co., Inc. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7425655-B2 | Mono di & tri cyclic compounds useful for lowering IgE concentrations | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-09-16 | — | — | US | disclosed |
| US-7425655-B2 | Mono di & tri cyclic compounds useful for lowering IgE concentrations | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-09-16 | — | — | US | disclosed |
| WO-2008060488-A1 | TRICYCLIC HETEROAROMATIC COMPOUNDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| US-4466977-A | N-[2-Amino(oxy- or thia- group-substituted-cycloaliphatic)]benzeneacetamides and -benzamide analgesics | THE UPJOHN COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| EP-0108602-A1 | N-(2-aminocycloalkyl)benzamide and benzeneacetamide derivatives | THE UPJOHN COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |
| US-4360531-A | Substituted cycloalkanes | THE UPJOHN COMPANY (US) | 1982-11-23 | — | — | US | disclosed |