SCHEMBL4383348

SCHEMBL4383348

C=C(C)C(=O)OCCC(C)(OP(=O)(O)O)[N+](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028453 0.79 TSHR (0.40) THRBTSHRALDH1A1
Trimethylammonium SCHEMBL27849604 0.78 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL19185656 0.77 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL27907144 0.76 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL27550726 0.76 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL27903855 0.76 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL28254462 0.74 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4070069 0.72 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL438464 0.71 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8965485 0.71 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106461682-B The enzymatic of HbA1c measures 德赛诊断系统有限公司 2018-09-21 CN claimed
CN-106574933-A Enzymatic determination of HbA1c 德赛诊断系统有限公司 2017-04-19 CN claimed
CN-106461682-A Enzymatic determination of hba1c 德赛诊断系统有限公司 2017-02-22 CN claimed
CN-106461682-B The enzymatic of HbA1c measures 德赛诊断系统有限公司 2018-09-21 CN disclosed
CN-107428824-A PDGF/VEGF dual antagonists 科达制药 2017-12-01 CN disclosed
CN-106574933-A Enzymatic determination of HbA1c 德赛诊断系统有限公司 2017-04-19 CN disclosed
CN-106461682-A Enzymatic determination of hba1c 德赛诊断系统有限公司 2017-02-22 CN disclosed
EP-2751153-A1 METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS Vertellus Specialties Inc. (US) 2014-07-09 EP disclosed
CN-103492489-A High molecular weight zwitterionic polymers OLIGASIS 2014-01-01 CN disclosed
WO-2013033553-A1 METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS VERTELLUS SPECIALTIES INC. (US) 2013-03-07 WO disclosed
US-8252878-B2 Polymer BIOCOMPATIBLES UK LIMITED (GB) 2012-08-28 US disclosed
EP-2041196-A2 POLYMER Biocompatibles UK Limited (GB) 2009-04-01 EP disclosed
WO-2008006912-A2 POLYMER BIOCOMPATIBLES UK LIMITED (GB) 2008-01-17 WO disclosed
US-20040176556-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2004-09-09 US disclosed
US-20030190405-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2003-10-09 US disclosed
US-6251964-B1 CATIONIC TERPOLYMER BIOCOMPATIBLES LIMITED (GB) 2001-06-26 US disclosed
EP-0866815-B1 BIOCOMPATIBLE COMPOSITIONS BIOCOMPATIBLES LTD (GB) 2000-02-23 EP disclosed
EP-0866815-A3 BIOCOMPATIBLE COMPOSITIONS BIOCOMPATIBLES LIMITED (GB) 1998-10-21 EP disclosed
EP-0866815-A2 BIOCOMPATIBLE COMPOSITIONS BIOCOMPATIBLES LIMITED (GB) 1998-09-30 EP disclosed
WO-1998022516-A1 BIOCOMPATIBLE COMPOSITIONS BIOCOMPATIBLES LIMITED (GB) 1998-05-28 WO disclosed