Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388559 | 0.93 | HRH3 (0.61) | HRH3 | |
| SCHEMBL4389011 | 0.88 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4383770 | 0.84 | HRH3 (0.47) | HRH3 | |
| SCHEMBL4388044 | 0.83 | HRH3 (0.40) | HRH3 | |
| SCHEMBL4383998 | 0.83 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL4384000 | 0.83 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL4391281 | 0.83 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL13788007 | 0.82 | HRH3 (0.46) | HRH3 | |
| SCHEMBL4390856 | 0.81 | HRH3 (0.45) | HRH3 | |
| SCHEMBL4388482 | 0.81 | HRH3 (0.45) | HRH3DRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | HRH3 452/4885DRD3 126/4885KCNH2 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.