Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036187 | 0.88 | CYP3A4 (0.46) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4885955 | 0.84 | KMT2A (0.49) | CYP1A2CYP3A4SLC6A3ALDH1A1KDM4E | |
| SCHEMBL6796070 | 0.83 | KDM4E (0.47) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2656952 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20993622 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL29658491 | 0.83 | KDM4E (0.47) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20993625 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1534974 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3767996 | 0.83 | SLC6A3 (0.52) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL23042521 | 0.82 | CYP1A2 (0.44) | CYP1A2CYP3A4SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-9695126-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | US | disclosed |
| US-9398767-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-26 | — | — | US | disclosed |
| EP-3000809-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2430000-B1 | Fungicide pyrazole carboxamide derivates | BAYER IP GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2049528-B1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| CN-103172570-B | Mycocide N-6 unit condenses (mixing) aryl-methylene-N-cycloalkyl carboxamide derivatives | BAYER CROPSCIENCE SA (DE) | 2015-09-30 | — | — | CN | disclosed |
| US-8772266-B2 | Fungicide pyrazole carboxamides derivates | BAYER CROPSCIENCE AG (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG | 2014-05-29 | — | — | US | disclosed |
| WO-2009016220-A1 | FUNGICIDAL N-CYCLOALKYL-BENZYL-THIOCARBOXAMIDES OR N-CYCLOALKYL-BENZYL-N' -SUBSTITUTED-AMIDINE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009016221-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009016219-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-THIO CARBOXAMIDE OR 2-PYRIDYL-METHYLENE-N-SUBSTITUTED CARBOXIMIDAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | disclosed |
| CN-101175750-A | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER CROPSCIENCE SA (FR) | 2008-05-07 | — | — | CN | disclosed |
| CN-101175750-A | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER CROPSCIENCE SA (FR) | 2008-05-07 | — | — | CN | disclosed |
| WO-2008015189-A2 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-02-07 | — | — | WO | disclosed |
| EP-1881978-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-30 | — | — | EP | disclosed |
| EP-1881978-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120224-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006120224-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | CYP1A2 48/4885CYP3A4 52/4885SLC6A3 4731/4885 |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | CYP1A2 48/4885CYP3A4 52/4885SLC6A3 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.