Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169067 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL4623160 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL775490 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL231822 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL29419093 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL29419078 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL29419132 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL122901 | 0.87 | GAA (0.40) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL1274327 | 0.86 | GAA (0.42) | GAAMEN1KMT2AKDM4ECCR1 | |
| SCHEMBL1274329 | 0.86 | GAA (0.42) | GAAMEN1KMT2AKDM4ECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464630-B1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| US-8748420-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8604040-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2576539-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-8367844-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011147765-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | GAA 1298/4885MEN1 412/4885KMT2A 3169/4885 |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | GAA 1214/4885MEN1 428/4885KMT2A 3300/4885 |
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CBR3 | GAA 3965/4885MEN1 2163/4885KMT2A 4420/4885 |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CX3CR1 | GAA 4083/4885MEN1 2183/4885KMT2A 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.