Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801451 | 0.78 | ESR1 (0.43) | ALDH1A1MAPTKDM4EHPGDGAA | |
| SCHEMBL1800673 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL1803361 | 0.74 | RIPK2 (0.44) | ALDH1A1TLR8DPP4LMNASLC9A5 | |
| SCHEMBL33720 | 0.70 | HTT (0.44) | ALDH1A1MAPTKDM4EGAANR1I2 | |
| SCHEMBL1799813 | 0.70 | KMT2A (0.58) | ALDH1A1MAPTKDM4EHPGDGAA | |
| Hydrochloric Acid SCHEMBL6278290 | 0.69 | HTT (0.42) | ALDH1A1MAPTKDM4EGAANR1I2 | |
| SCHEMBL15428612 | 0.68 | ADORA2A (0.42) | ALDH1A1MAPTKDM4EHPGDADORA2A | |
| SCHEMBL1720030 | 0.67 | POLB (0.66) | ALDH1A1MAPTKDM4EHPGDGAA | |
| SCHEMBL20075630 | 0.67 | MEN1 (0.41) | ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL15428611 | 0.66 | JAK2 (0.46) | ALDH1A1KDM4EDPP4ATMJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345580-B9 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2009-11-25 | — | — | EP | claimed |
| EP-1345580-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2006-06-07 | — | — | EP | claimed |