Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.89 |
| ▸ | CCR8 | P51685 | 2/20 | 0.89 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4388984 | 0.94 | CCR1 (0.89) | CCR1CCR8METAP2CYP2A6NOS3 | |
| Hydrochloric Acid SCHEMBL2410509 | 0.94 | CCR1 (0.89) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL29388304 | 0.94 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL30511194 | 0.94 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL196966 | 0.94 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL29751933 | 0.92 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL3423401 | 0.92 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL20557390 | 0.92 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL29751919 | 0.92 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL3422291 | 0.92 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629431-B2 | Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20080064847-A1 | Oxidative carbonylation; molecular weight control | IDEMISU KOSAN CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |