SCHEMBL3423401

SCHEMBL3423401

Cc1cccc(-c2cccc(-c3cccc(C)n3)n2)n1

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.94
CCR8 P51685 2/20 0.94
METAP2 P50579 1/20 0.59
CYP2A6 P11509 1/20 0.54
NOS3 P29474 1/20 0.52
NOS2 P35228 1/20 0.52
KDM4E B2RXH2 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
TP53 P04637 2/20 0.46
ALOX15 P16050 2/20 0.46
LMNA P02545 1/20 0.46
ALPL P05186 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
CCR5 P51681 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422291 1.00 CCR1 (0.94) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL29388304 0.97 CCR1 (1.00) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL196966 0.97 CCR1 (1.00) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL30511194 0.97 CCR1 (1.00) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL29751919 0.94 CCR1 (0.94) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL20557390 0.94 CCR1 (0.94) CCR1CCR8METAP2CYP2A6NOS3
SCHEMBL29751933 0.94 CCR1 (0.94) CCR1CCR8METAP2CYP2A6NOS3
Bromide SCHEMBL4388984 0.92 CCR1 (0.89) CCR1CCR8METAP2CYP2A6NOS3
Hydrochloric Acid SCHEMBL2410509 0.92 CCR1 (0.89) CCR1CCR8METAP2CYP2A6NOS3
Iodide SCHEMBL4384044 0.92 CCR1 (0.89) CCR1CCR8METAP2CYP2A6NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454042-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-10-22 US disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-7282581-B2 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2007-10-16 US disclosed
US-7282581-B2 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2007-10-16 US disclosed
US-7259229-B2 Electroactive fluorene polymers having perfluoralkyl groups, process for preparing such polymers and devices made with such polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-21 US disclosed
US-7259229-B2 Electroactive fluorene polymers having perfluoralkyl groups, process for preparing such polymers and devices made with such polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-21 US disclosed
US-7230070-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-12 US disclosed
US-7230070-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-12 US disclosed
US-7214763-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-08 US disclosed
US-7183365-B2 Electroactive fluorene polymers having perfluoroalkyl groups, process for preparing such polymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-27 US disclosed
US-7183366-B2 Aromatic copolymers from dihalofluorene compounds and another dihalo- or diborono- aromatic monomers; organic electroluminescent polymers for use in light-emitting diodes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-27 US disclosed
WO-2000053642-A1 CONTROLLED (CO)POLYMERISATION WITH N-HETEROCYCLES METAL COMPLEX SYSTEMS SCHUBERT ULRICH S (DE) 2000-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 CCR1 3230/4885CCR8 4074/4885METAP2 1122/4885
US-10454042-B2 Organic electroluminescence device EML4, ELOC, ORC3 CCR1 3292/4885CCR8 3738/4885METAP2 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.