SCHEMBL4384457

SCHEMBL4384457

ClP(Cl)c1ccccc1.ClP(Cl)c1ccccc1.ClP(Cl)c1ccccc1.Cl[Ru]Cl

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ESR1 P03372 4/20 0.35
ESR2 Q92731 4/20 0.35
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TRPA1 O75762 1/20 0.33
GSK3B P49841 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CES1 P23141 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28067265 0.91 TDP1 (0.53) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL246946 0.91
SCHEMBL29126140 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
Phosphine SCHEMBL28842294 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL28208589 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL28000859 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL3838680 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL21518321 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
Hydrochloric Acid SCHEMBL22230523 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1
SCHEMBL27914446 0.88 TDP1 (0.50) CYP3A4TDP1ESR1ESR2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045280-B1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-10-10 EP disclosed
EP-1950216-B1 PROCESS FOR PRODUCING ORGANIC TRANSITION METAL COMPLEX COMPOUND MITSUI CHEMICALS INC (JP) 2018-08-29 EP disclosed
US-8450440-B2 Method for purifying polymer and polymer MITSUI CHEMICALS, INC. (JP) 2013-05-28 US disclosed
US-20120208976-A1 METHOD FOR PURIFYING POLYMER AND POLYMER MITSUI CHEMICALS, INC (JP) 2012-08-16 US disclosed
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed
EP-1275676-B1 HYDROGENATED RING-OPENING METATHESIS COPOLYMER AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS INC (JP) 2008-05-07 EP disclosed
US-7081501-B2 Hydrogenated ring-opening metathesis polymer and process for producing the same MITSUI CHEMICALS, INC. (JP) 2006-07-25 US disclosed
EP-1298156-B1 FLUORINATED CYCLOOLEFIN POLYMERS, PROCESSES FOR THEIR PREPARATION AND THEIR USE MITSUI CHEMICALS INC (JP) 2005-08-17 EP disclosed
EP-1538173-A1 Hydrogenated ring-opening metathesis polymer and process for producing the same Mitsui Chemicals, Inc. (JP) 2005-06-08 EP disclosed
US-20050119412-A1 Hydrogenated ring-opening metathesis polymer and process for producing the same MITSUI CHEMICALS, INC. (JP) 2005-06-02 US disclosed
US-6800720-B2 BASE POLYMER CONTAINING AN ESTER GROUP TO BE DECOMPOSED TO A CARBOXYLIC ACID TO BECOME SOLUBLE IN THE DEVELOPER FOR A PHOTORESIST USED IN FINE WORKING OF A SEMICONDUCTOR USING ULTRAVIOLET RAY; HEAT RESISTANCE; OPTICS; ADHESION MITSUI CHEMICALS, INC. (JP) 2004-10-05 US disclosed
EP-1298156-A1 FLUORINATED CYCLOOLEFIN POLYMERS, PROCESSES FOR PREPARATION OF FLUORINATED CYCLOOLEFIN MONOMERS AND POLYMERS THEREOF, AND USE OF THE SAME Mitsui Chemicals, Inc. (JP) 2003-04-02 EP disclosed
EP-1275676-A1 HYDROGENATED RING-OPENING METATHESIS COPOLYMER AND PROCESS FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2003-01-15 EP disclosed
US-20020165328-A1 Hydrogenated ring-opening metathesis copolymer and process for producing the same MITSUI CHEMICALS, INC. (JP) 2002-11-07 US disclosed
US-6372854-B1 POLYALKENAMERS USED AS PHOTORESISTS HAVING EXCELLENT OPTICAL ELECTRICAL PROPERTIES; HIGH RIGIDITY; HEAT RESISTANCE; ADHESION AND WEAR RESISTANCE; HYDROGENATION; ACIDOLYSIS MITSUI CHEMICALS, INC. (JP) 2002-04-16 US disclosed
US-6197894-B1 IN THE PRESENCE OF HYDROGEN USING A CATALYST CONSISTING OF AN AMINE COMPOUND AND A METALLIC COMPLEX OF AN ORGANIC PHOSPHOROUS COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-03-06 US disclosed