Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246946 | 1.00 | — | — | |
| Phosphine SCHEMBL28842294 | 0.97 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL21518321 | 0.97 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2TSHR | |
| Hydrochloric Acid SCHEMBL22230523 | 0.97 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL3838680 | 0.97 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL29126140 | 0.97 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL28863018 | 0.91 | CYP3A4 (0.71) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL4384457 | 0.91 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2TSHR | |
| Toluene SCHEMBL29005933 | 0.86 | ACHE (0.58) | TDP1CYP3A4ESR1ESR2TSHR | |
| Urea SCHEMBL11427023 | 0.84 | MAPT (0.44) | TDP1CYP3A4ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732708-A | Method for producing dichlorophenylphosphine | 东营美利达新型材料科技有限公司 | 2016-07-06 | — | — | CN | disclosed |