Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.84 |
| ▸ | ADORA2A | P29274 | 18/20 | 0.84 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.84 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395638 | 1.00 | ADORA3 (0.84) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4384713 | 1.00 | ADORA3 (0.84) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4382482 | 0.93 | ADORA3 (0.81) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4382516 | 0.92 | ADORA3 (0.84) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4387417 | 0.91 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL31061129 | 0.91 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4387697 | 0.89 | ADORA3 (0.80) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL19464857 | 0.89 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4386132 | 0.88 | ADORA3 (0.66) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4392810 | 0.86 | ADORA3 (0.82) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537135-B1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS INC (US) | 2009-11-25 | — | — | EP | disclosed |