SCHEMBL4385197

SCHEMBL4385197

COC(=O)c1ccccc1OC(=O)OCO

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.59
KMT2A Q03164 3/20 0.56
HTT P42858 1/20 0.56
KDM4E B2RXH2 3/20 0.54
HSD17B10 Q99714 2/20 0.54
HPGD P15428 1/20 0.54
MAPT P10636 1/20 0.51
SLC6A4 P31645 2/20 0.50
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
GLA P06280 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CFTR P13569 1/20 0.46
ATM Q13315 2/20 0.46
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7116138 0.91 SLC6A3 (0.52) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL4391331 0.87 SLC6A3 (0.59) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL29551673 0.86 SLC6A3 (0.71) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL47893 0.86 SLC6A3 (0.71) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL22355995 0.86 SLC6A3 (0.58) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL4393207 0.84 HSD17B10 (0.73) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL132171 0.83 SLC6A3 (0.55) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL133634 0.83 SLC6A3 (0.55) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL5706157 0.83 SLC6A3 (0.72) SLC6A3KMT2AHTTKDM4EHSD17B10
SCHEMBL4389489 0.83 HSD17B10 (0.55) SLC6A3KMT2AKDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 SLC6A3 839/4885KMT2A 2526/4885HTT 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.