Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385395 | 1.00 | LMNA (0.31) | LMNACHRM2CHRM3BTN3A1 | |
| SCHEMBL4385390 | 1.00 | LMNA (0.31) | LMNACHRM2CHRM3BTN3A1 | |
| SCHEMBL4389289 | 0.89 | SMYD2 (0.33) | CHRM2CHRM3 | |
| SCHEMBL4389296 | 0.89 | SMYD2 (0.33) | CHRM2CHRM3 | |
| SCHEMBL4389293 | 0.89 | SMYD2 (0.33) | CHRM2CHRM3 | |
| SCHEMBL4396881 | 0.83 | CHRM3 (0.32) | CHRM2CHRM3 | |
| SCHEMBL4389060 | 0.83 | CHRM3 (0.32) | CHRM2CHRM3 | |
| SCHEMBL4386025 | 0.83 | CHRM3 (0.32) | CHRM2CHRM3 | |
| SCHEMBL4386023 | 0.83 | CHRM3 (0.32) | CHRM2CHRM3 | |
| SCHEMBL4396877 | 0.83 | CHRM3 (0.32) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-1889835-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | CBR3, CNR1, C3AR1 | LMNA 1421/4885CHRM2 13/4885CHRM3 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.