Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.59 |
| ▸ | MMP9 | P14780 | 10/20 | 0.59 |
| ▸ | MMP13 | P45452 | 4/20 | 0.59 |
| ▸ | MMP14 | P50281 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP3 | P08254 | 2/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54973 | 1.00 | MMP2 (0.59) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL48808 | 1.00 | MMP2 (0.59) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL48807 | 1.00 | MMP2 (0.59) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL49184 | 0.88 | MMP2 (0.63) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL49185 | 0.88 | MMP2 (0.63) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL49193 | 0.88 | MMP2 (0.63) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL4383081 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL4382194 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL49295 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL49294 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP13MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735274-B1 | NONPEPTIDE INHIBITORS OF MATRIX METALLOPROTEINASES | SOUTHERN RES INST (US) | 2009-11-25 | — | — | EP | disclosed |