Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996623 | 0.92 | FAAH (0.55) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL844472 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL14040614 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL1721285 | 0.88 | FAAH (0.47) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL4096169 | 0.87 | POLB (0.51) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL16465122 | 0.87 | FAAH (0.49) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL27648565 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL6249904 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL6190128 | 0.86 | FAAH (0.48) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL4651068 | 0.85 | FAAH (0.47) | SMN1; SMN2NPC1RAB9AFAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121676-A1 | PREPERATION AND UTILITY OF CCR5 INHIBITORS | Auspex Pharmaceuticals, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008077103-A1 | PREPERATION AND UTILITY OF CCR5 INHIBITORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| CN-101107265-A | Cyclic nonapeptide amides | AICURIS GMBH & CO KG (DE) | 2008-01-16 | — | — | CN | disclosed |