Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219216 | 0.87 | MAPT (0.43) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL6828592 | 0.86 | ABL1 (0.50) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL30207665 | 0.84 | MEN1 (0.46) | MAPTKDM4EALDH1A1HPGDBACE1 | |
| SCHEMBL28973245 | 0.84 | MEN1 (0.46) | MAPTKDM4EALDH1A1HPGDBACE1 | |
| SCHEMBL8984737 | 0.83 | PGR (0.47) | MAPTKDM4EALDH1A1HPGDPGR | |
| SCHEMBL30150694 | 0.82 | ADORA2A (0.45) | MAPTKDM4EALDH1A1HPGDPGR | |
| SCHEMBL29766669 | 0.82 | ADORA2A (0.47) | MAPTKDM4EALDH1A1HPGDPGR | |
| SCHEMBL150217 | 0.82 | ADORA2A (0.47) | MAPTKDM4EALDH1A1HPGDPGR | |
| Ammonia Solution, Strong SCHEMBL28343573 | 0.81 | PGR (0.46) | MAPTKDM4EALDH1A1HPGDPGR | |
| SCHEMBL29558487 | 0.81 | NCOA1 (0.44) | MAPTKDM4EALDH1A1HPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629429-B2 | Aromatic resin; optical device; overcoating substrate with polymer; charge transfer compound, charge generating compoind | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-12-08 | — | — | US | disclosed |
| US-20040158017-A1 | Substituted fluorene polymers their preparation and uses | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-08-12 | — | — | US | disclosed |
| EP-1385919-B1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2004-08-11 | — | — | EP | disclosed |