SCHEMBL4385826

SCHEMBL4385826

Cc1cccc(Cl)c1.[Ru].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACHE P22303 4/20 0.41
NPSR1 Q6W5P4 1/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
KCNK3 O14649 1/20 0.37
KCNK9 Q9NPC2 1/20 0.37
TSHR P16473 3/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
HSP90AA1 P07900 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50087 0.83 TDP1 (0.60) CYP3A4TDP1ACHENPSR1ESR1
SCHEMBL29535020 0.83 TDP1 (0.60) CYP3A4TDP1ACHENPSR1ESR1
SCHEMBL50019 0.83 TDP1 (0.60) CYP3A4TDP1ACHENPSR1ESR1
SCHEMBL9854467 0.81 TDP1 (0.57) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL6202698 0.81
SCHEMBL29567354 0.81
SCHEMBL12595 0.81
SCHEMBL187175 0.79
Methane SCHEMBL29230318 0.79
Bromide SCHEMBL28516239 0.79 ACHE (0.58) TDP1ACHEESR2KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045280-B1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-10-10 EP disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed