Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679224 | 0.84 | NPC1 (0.42) | KDM4ENPC1RAB9APKMNPSR1 | |
| SCHEMBL6099838 | 0.84 | NPSR1 (0.52) | KDM4EPKMNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28899641 | 0.79 | HTT (0.44) | NPSR1ALDH1A1MAPTHTT | |
| Malonic Acid SCHEMBL6672043 | 0.78 | NPSR1 (0.46) | KDM4EPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL18381305 | 0.75 | CA1 (0.45) | KDM4ENPC1RAB9APKMALDH1A1 | |
| SCHEMBL18381334 | 0.73 | HDAC3 (0.40) | KDM4ENPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL16252212 | 0.72 | MAPK1 (0.38) | KDM4ERAB9APKMNPSR1SMN1; SMN2 | |
| SCHEMBL7270380 | 0.72 | TSHR (0.40) | KDM4EPKMNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16889110 | 0.72 | — | — | |
| SCHEMBL6683078 | 0.71 | TAAR1 (0.41) | KDM4ENPC1RAB9APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| WO-2000032590-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-06-08 | — | — | WO | disclosed |