Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099838 | 0.93 | NPSR1 (0.52) | NPSR1KDM4CKDM4EGPR142KMT2A | |
| SCHEMBL17025004 | 0.80 | KDM4C (0.51) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| SCHEMBL4385833 | 0.78 | KDM4E (0.42) | NPSR1KDM4CKDM4EMAPK1PKM | |
| SCHEMBL17038776 | 0.76 | PDE10A (0.45) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| SCHEMBL20024587 | 0.76 | KDM4C (0.48) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| SCHEMBL4779863 | 0.76 | LMNA (0.44) | NPSR1KDM4CKDM4EGPR142KMT2A | |
| SCHEMBL30223118 | 0.75 | KDM4C (0.47) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| SCHEMBL12265803 | 0.75 | KDM4C (0.43) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| Malonic Acid SCHEMBL6672041 | 0.72 | KDM4C (0.39) | NPSR1KDM4CKDM4EGPR142ADORA2A | |
| SCHEMBL8077417 | 0.72 | HPGD (0.46) | NPSR1KDM4CKDM4EGPR142KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069118-B1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6506903-B1 | By reacting 4-methylthiazole with N-halosuccinimide in solvent in presence of 2,2-azobisisobutyronitrile; halogenation, catalysis | SHIONOGI & CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1069118-A1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |