Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.32 |
| ▸ | LDHB | P07195 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996574 | 0.82 | KDM4E (0.35) | FFAR1KDM4ELDHALDHB | |
| SCHEMBL11364780 | 0.82 | KDM4E (0.35) | FFAR1KDM4ELDHALDHBALDH1A1 | |
| SCHEMBL12936374 | 0.79 | FFAR1 (0.46) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL10019207 | 0.76 | FFAR1 (0.50) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL12088398 | 0.76 | KDM4E (0.47) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL15698070 | 0.73 | FFAR1 (0.38) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL1259455 | 0.72 | LDHA (0.34) | KDM4EGAALMNALDHALDHB | |
| SCHEMBL238022 | 0.72 | LDHA (0.48) | KDM4ELDHALDHBNPSR1CYP3A4 | |
| SCHEMBL3735175 | 0.72 | CYP3A4 (0.47) | LMNALDHALDHBCYP3A4MEN1 | |
| SCHEMBL10137794 | 0.71 | FFAR1 (0.45) | FFAR1KDM4EDBHGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | claimed |
| EP-1689229-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | United States Army Medical Research and Materiel Command (US) | 2006-08-16 | — | — | EP | claimed |
| WO-2005046329-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | UNITED STATES MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2005-05-26 | — | — | WO | claimed |
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | ARMY, UNITED STATES | 2005-05-12 | — | — | US | claimed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1689229-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | United States Army Medical Research and Materiel Command (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005046329-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | UNITED STATES MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | ARMY, UNITED STATES | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | TYR, ABCG2, CHIA | FFAR1 1465/4885KDM4E 2351/4885DBH 1582/4885 |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | TYR, ABCG2, CHIA | FFAR1 1465/4885KDM4E 2351/4885DBH 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.