Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476959 | 0.87 | CXCR4 (0.35) | CXCR4 | |
| SCHEMBL2501820 | 0.86 | CXCR4 (0.41) | CXCR4 | |
| SCHEMBL15387266 | 0.84 | CXCR4 (0.33) | CXCR4 | |
| SCHEMBL11903970 | 0.77 | GAA (0.40) | CXCR4 | |
| SCHEMBL4239716 | 0.76 | HDAC6 (0.37) | CXCR4 | |
| SCHEMBL11904119 | 0.76 | P2RX3 (0.30) | — | |
| SCHEMBL11904802 | 0.75 | CXCR4 (0.32) | CXCR4 | |
| SCHEMBL8301709 | 0.74 | CXCR4 (0.40) | CXCR4 | |
| SCHEMBL2474527 | 0.72 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL8306813 | 0.72 | CXCR4 (0.39) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550484-B2 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy | GENZYME CORPORATION (US) | 2009-06-23 | — | — | US | disclosed |