Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.60 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663247 | 0.85 | NR3C1 (0.56) | NR3C1CCR1CYP17A1CYP1A2 | |
| SCHEMBL4397360 | 0.85 | NR3C1 (0.61) | NR3C1 | |
| SCHEMBL476811 | 0.83 | NR3C1 (0.69) | NR3C1 | |
| SCHEMBL12663246 | 0.82 | NR3C1 (0.54) | NR3C1CCR1 | |
| SCHEMBL476762 | 0.81 | NR3C1 (0.67) | NR3C1 | |
| SCHEMBL12663027 | 0.77 | NR3C1 (0.56) | NR3C1CYP17A1CYP1A2 | |
| SCHEMBL4381531 | 0.75 | NR3C1 (0.59) | NR3C1 | |
| SCHEMBL4390636 | 0.75 | NR3C1 (0.53) | NR3C1 | |
| SCHEMBL476760 | 0.75 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL4106128 | 0.75 | NR3C1 (0.54) | NR3C1CCR1CYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |