Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385762 | 0.90 | TRPV1 (0.58) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4388633 | 0.85 | TRPV1 (1.00) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL29386356 | 0.85 | TRPV1 (1.00) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL5934166 | 0.82 | TRPV1 (0.70) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4968206 | 0.77 | TRPV1 (0.60) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4384186 | 0.77 | TRPV1 (0.81) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4386968 | 0.77 | RAB9A (0.62) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4920329 | 0.77 | TRPV1 (0.65) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4386354 | 0.76 | TRPV1 (0.76) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4970699 | 0.75 | TRPV1 (0.60) | TRPV1RAB9ANPC1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606289-B1 | CARBOXAMIDE DERIVATIVES | GLAXO GROUP LTD (GB) | 2009-12-02 | — | — | EP | claimed |
| EP-1606289-B1 | CARBOXAMIDE DERIVATIVES | GLAXO GROUP LTD (GB) | 2009-12-02 | — | — | EP | disclosed |