Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384793 | 0.94 | EGFR (0.35) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL2864914 | 0.92 | EGFR (0.37) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4379783 | 0.87 | EGFR (0.36) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4383991 | 0.87 | EGFR (0.39) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4386891 | 0.86 | EGFR (0.41) | EGFR | |
| SCHEMBL4392489 | 0.85 | F2RL3 (0.36) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4387418 | 0.84 | EGFR (0.44) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4379902 | 0.84 | EGFR (0.39) | EGFRMAPTL3MBTL1TDP1 | |
| SCHEMBL4384966 | 0.84 | EGFR (0.35) | EGFRTDP1 | |
| SCHEMBL4379817 | 0.84 | EGFR (0.40) | EGFRMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | EGFR 624/4885MAPT 2443/4885L3MBTL1 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.