Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441293 | 0.95 | MEN1 (0.59) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL1753930 | 0.95 | MEN1 (0.59) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL10032304 | 0.93 | MEN1 (0.56) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL30870477 | 0.93 | MEN1 (0.56) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL17899333 | 0.93 | MEN1 (0.56) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL30870479 | 0.93 | MEN1 (0.56) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL20250404 | 0.91 | MEN1 (0.54) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL20250342 | 0.91 | MEN1 (0.54) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL30595380 | 0.91 | MEN1 (0.54) | RAB9AMEN1KMT2APARP1ADORA2A | |
| SCHEMBL10032371 | 0.91 | MEN1 (0.54) | RAB9AMEN1KMT2APARP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629431-B2 | Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20080064847-A1 | Oxidative carbonylation; molecular weight control | IDEMISU KOSAN CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |