Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD81 | P60033 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11253194 | 0.85 | CD81 (0.31) | CD81 | |
| SCHEMBL8673613 | 0.83 | CD81 (0.37) | CD81PPARGBACE1 | |
| SCHEMBL45793 | 0.82 | — | — | |
| SCHEMBL16092 | 0.82 | — | — | |
| SCHEMBL28832685 | 0.82 | CD81 (0.41) | CD81PPARGBACE1 | |
| Acrylic Acid SCHEMBL2403766 | 0.81 | LMNA (0.42) | CD81PPARGBACE1 | |
| Ethylene Glycol SCHEMBL28863335 | 0.80 | CD81 (0.40) | CD81PPARGBACE1 | |
| Acetone SCHEMBL8337338 | 0.80 | CD81 (0.40) | CD81PPARGBACE1 | |
| SCHEMBL28531941 | 0.80 | CD81 (0.40) | CD81PPARGBACE1 | |
| Phosphine SCHEMBL28166002 | 0.80 | CD81 (0.40) | CD81PPARGBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101698-B2 | Surface active prepolymers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2012-01-24 | — | — | US | disclosed |
| US-8071704-B2 | Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110172374-A1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH HEALTH HOLDCO LIMITED (IE) | 2011-07-14 | — | — | US | disclosed |
| US-7935770-B2 | Surface active prepolymers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2162474-B1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB (US) | 2011-01-19 | — | — | EP | disclosed |
| EP-2162474-A1 | NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS | Bausch & Lomb Incorporated (US) | 2010-03-17 | — | — | EP | disclosed |
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2009-04-09 | — | — | US | disclosed |
| WO-2009045886-A1 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2009-04-09 | — | — | WO | disclosed |
| US-7482416-B2 | Prepolymers for improved surface modification of contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2009-01-27 | — | — | US | disclosed |
| US-20090012250-A1 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED | 2009-01-08 | — | — | US | disclosed |
| US-7176268-B2 | Prepolymers for improved surface modification of contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2007-02-13 | — | — | US | disclosed |
| EP-1706438-A1 | NOVEL PREPOLYMERS FOR IMPROVED SURFACE MODIFICATION OF CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2006-10-04 | — | — | EP | disclosed |
| US-20060217454-A1 | Surface modification of contact lenses | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2006-09-28 | — | — | US | disclosed |
| US-7084188-B2 | Surface modification of contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2006-08-01 | — | — | US | disclosed |
| WO-2006007252-A1 | NOVEL PREPOLYMERS FOR IMPROVED SURFACE MODIFICATION OF CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2006-01-19 | — | — | WO | disclosed |
| US-20050288466-A1 | Novel prepolymers for improved surface modification of contact lenses | BAUSCH HEALTH US, LLC | 2005-12-29 | — | — | US | disclosed |
| WO-2005056651-A1 | IMPROVED SURFACE MODIFICATION OF CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056625-A1 | NOVEL PREPOLYMERS FOR IMPROVED SURFACE MODIFICATION OF CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20050124776-A1 | Novel prepolymers for improved surface modification of contact lenses | BAUSCH HEALTH AMERICAS, INC. | 2005-06-09 | — | — | US | disclosed |
| US-20050124719-A1 | Surface modification of contact lenses | 1530065 B.C. LTD. (CA) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | NOTUM, ITK, MFAP1 | CD81 3749/4885PPARG 2152/4885BACE1 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.