SCHEMBL4387518

SCHEMBL4387518

CC1(C)CCCCCCCCCCCCCCCCCCCCCCCCOc2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.38
DRD1 P21728 1/20 0.38
SLC5A7 Q9GZV3 1/20 0.38
PKM P14618 1/20 0.36
TSHR P16473 1/20 0.36
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 2/20 0.32
CRHBP P24387 2/20 0.32
CRHR2 Q13324 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
MAP3K5 Q99683 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3520940 0.80 ITGB2 (0.43) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL12446304 0.73 ITGB2 (0.57) ADORA3DRD1SLC5A7PKMTSHR
SCHEMBL2632863 0.72 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL10987360 0.72 SMN1; SMN2 (0.56) ADORA3DRD1SLC5A7PKMTSHR
SCHEMBL3224040 0.70 SMN1; SMN2 (0.54) ADORA3DRD1SLC5A7PKMTSHR
SCHEMBL3253257 0.70 SMN1; SMN2 (0.54) ADORA3DRD1SLC5A7PKMTSHR
SCHEMBL8026963 0.69 ITGB2 (0.72) ITGB2ICAM1ITGALALDH1A1LMNA
SCHEMBL20831516 0.69 ITGB2 (0.72) PKMTSHRITGB2ICAM1ITGAL
SCHEMBL8020938 0.69 ITGB2 (0.72) ITGB2ICAM1ITGALALDH1A1LMNA
SCHEMBL8020827 0.69 ITGB2 (0.72) ITGB2ICAM1ITGALALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009051703-A1 ION-SELECTIVE SENSORS THE CHARLES STARK DRAPER LABORATORY, INC. (US) 2009-04-23 WO disclosed