Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253257 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL10987360 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3082540 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3072591 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3077321 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL12446304 | 0.91 | ITGB2 (0.57) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL8346859 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL11505174 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL23658082 | 0.84 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL30143827 | 0.84 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085474-A1 | Fluorinating reagents and their preparation | FLNA, ARFGEF1, FLNB | SMN1; SMN2 3109/4885LMNA 1526/4885CRHBP 4865/4885 |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | FLNA, ARFGEF1, FLNB | SMN1; SMN2 3109/4885LMNA 1526/4885CRHBP 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.