Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139885 | 0.88 | CNR2 (0.49) | CNR2CNR1MEN1TP53MAPT | |
| SCHEMBL1049677 | 0.87 | HTR2C (0.41) | CNR2CNR1HTR1AHTR1BMAPT | |
| SCHEMBL4399572 | 0.87 | CSNK2A1 (0.45) | CNR2CNR1KDM4EMEN1USP2 | |
| SCHEMBL3881130 | 0.81 | TAAR1 (0.42) | HTR1AHTR1BMAPT | |
| SCHEMBL20563650 | 0.81 | SMN1; SMN2 (0.50) | HTR1AHTR1BKDM4EMEN1USP2 | |
| SCHEMBL28282874 | 0.80 | CNR2 (0.45) | CNR2CNR1MEN1ALDH1A1TP53 | |
| SCHEMBL4363956 | 0.80 | MAOB (0.57) | — | |
| SCHEMBL2442358 | 0.79 | MAOB (0.55) | KDM4EMEN1USP2ALDH1A1TP53 | |
| SCHEMBL30118840 | 0.79 | MAOB (0.55) | KDM4EMEN1USP2ALDH1A1TP53 | |
| SCHEMBL9698367 | 0.77 | CNR2 (0.62) | CNR2CNR1MEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227390-B2 | Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090137434-A1 | BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF | AKEBONO BRAKE INDUSTRY CO., LTD (JP) | 2009-05-28 | — | — | US | disclosed |