Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.62 |
| ▸ | CNR1 | P21554 | 8/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | TYR | P14679 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139885 | 0.88 | CNR2 (0.49) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL4115449 | 0.83 | CNR2 (0.72) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL4108174 | 0.83 | CNR2 (0.72) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL4113024 | 0.83 | CNR2 (0.72) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL29111141 | 0.83 | CNR2 (0.54) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL4449940 | 0.83 | TYR (0.46) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL14557522 | 0.81 | SMPD1 (0.60) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL11329254 | 0.81 | SMPD1 (0.60) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL27696658 | 0.81 | TYR (0.54) | CNR2CNR1ALOX5TYRTSHR | |
| SCHEMBL8147933 | 0.80 | TYR (0.61) | CNR2CNR1ALOX5TYRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |