SCHEMBL4387787

SCHEMBL4387787

COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2OC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.53
P2RY14 Q15391 4/20 0.50
P2RY2 P41231 12/20 0.46
P2RY6 Q15077 10/20 0.46
SLC28A1 O00337 1/20 0.45
SLC28A2 O43868 1/20 0.45
SLC29A1 Q99808 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.45
P2RY4 P51582 6/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13589363 1.00 TYMP (0.53) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL10592428 0.94 TYMP (0.53) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL2584027 0.93 SLC28A1 (0.52) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL8390570 0.91 SLC28A1 (0.54) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL1317089 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL918582 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL918583 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL26502752 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL12434636 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1
SCHEMBL12513082 0.91 TYMP (0.62) TYMPP2RY14P2RY2P2RY6SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629447-B2 Dideoxynucleoside derivatives WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-12-08 US disclosed
US-20080064868-A1 Novel Dideoxynucleoside Derivatives WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064868-A1 Novel Dideoxynucleoside Derivatives DNA2, DDX20, DNASE1 TYMP 251/4885P2RY14 2886/4885P2RY2 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.