Pyridoxine

Pyridoxine

SCHEMBL43879

Cc1ncc(CO)c(CO)c1O.O=P(O)(O)O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Pyridoxine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.83
ALDH1A1 P00352 3/20 0.83
HPGD P15428 3/20 0.83
HSD17B10 Q99714 1/20 0.83
LMNA P02545 3/20 0.65
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
AOX1 Q06278 1/20 0.54
TRIM24 O15164 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
PDXK O00764 2/20 0.51
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
ESR1 P03372 1/20 0.46
PTGS1 P23219 1/20 0.46
ACP1 P24666 1/20 0.46
PDE4A P27815 1/20 0.46
P2RX1 P51575 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridoxine SCHEMBL29004449 1.00 KDM4E (0.83) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL31241297 0.98 KDM4E (0.80) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL28177480 0.98 KDM4E (0.80) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL1545934 0.98 KDM4E (0.80) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL15994725 0.97 KDM4E (0.77) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL30267871 0.91 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL2322958 0.91 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL30877002 0.91 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL3506 0.91 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10LMNA
Pyridoxine SCHEMBL28837806 0.89 KDM4E (0.89) KDM4EALDH1A1HPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081234-A Low-serum MSB1 suspension medium and chicken infectious anemia virus inactivated vaccine 2026-05-26 CN claimed
CN-122036796-A Method for high-selectivity synthesis of pyridoxine phosphate based on phase transfer catalytic system 台州职业技术学院 2026-05-15 CN claimed
CN-122036797-A Method for efficiently preparing high-purity pyridoxal phosphate by continuous flow 台州职业技术学院 2026-05-15 CN claimed
CN-120064663-A Metabolic marker for distinguishing hypertrophic cardiomyopathy and left ventricular hypertrophy and application 中国医学科学院阜外医院 2025-05-30 CN claimed
CN-119792284-A Application of vitamin B6 in preparing medicine for preventing and/or treating NLRP6 inflammation small body overactive state diseases 中国科学技术大学 2025-04-11 CN claimed
WO-2025038636-A1 ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS Vymedic, Inc. (US) 2025-02-20 WO claimed
US-20250057865-A1 ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS Vymedic, Inc. 2025-02-20 US claimed
CN-119082097-A Immobilized L-cysteine synthetase, and preparation method and application thereof 黑龙江新和成生物科技有限公司 2024-12-06 CN claimed
CN-118421548-A Construction method and application of recombinant strain for efficiently producing gamma-aminobutyric acid at food level 江南大学 2024-08-02 CN claimed
CN-118021982-A Pharmaceutical composition containing mineralocorticoid receptor antagonist and B vitamins 深圳奥萨制药有限公司 2024-05-14 CN claimed
EP-0495270-B1 Azaribine composition DRELL WILLIAM DR (US) 1996-01-03 EP claimed
EP-0461731-B1 Synthetic prosthetogens and their use in enzyme linked assays LONDON BIOTECHNOLOGY LTD (GB) 1994-07-13 EP claimed
EP-0495270-A1 Azaribine composition Drell, William, Dr. (US) 1992-07-22 EP claimed
EP-0156641-B1 ENZYMIC METHOD OF DETECTING ANALYTES AND NOVEL SUBSTRATES THEREFOR London Biotechnology Limited (GB) 1992-06-10 EP claimed
EP-0461731-A2 Synthetic prosthetogens and their use in enzyme linked assays LONDON BIOTECHNOLOGY LIMITED (GB) 1991-12-18 EP claimed
US-5057412-A Cleaving pyrimidine rionucleoside diester producing coeneyme for further reaction LONDON BIOTECHNOLOGY LIMITED (GB) 1991-10-15 US claimed
US-5023083-A Azarbine composition DRELL WILLIAM (US) 1991-06-11 US claimed
EP-0379936-A2 Pyridoxal for use in enzyme deficiencies, and a diagnostic kit for their diagnosis VESTA MEDICINES (PROPRIETARY) LIMITED (ZA) 1990-08-01 EP claimed
US-4745054-A ENZYME LABELS LONDON BIOTECHNOLOGY LIMITED (GB) 1988-05-17 US claimed
EP-0156641-A2 Enzymic method of detecting analytes and novel substrates therefor London Biotechnology Limited (GB) 1985-10-02 EP claimed