SCHEMBL4387913

SCHEMBL4387913

O=C(Oc1ccccc1)c1cccc(O)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.76
HPGD P15428 6/20 0.76
ALOX15 P16050 3/20 0.76
MAPT P10636 5/20 0.61
KDM4E B2RXH2 5/20 0.61
TDP1 Q9NUW8 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.58
LMNA P02545 3/20 0.58
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
CHRM1 P11229 1/20 0.58
TBXA2R P21731 1/20 0.58
SLC6A2 P23975 1/20 0.58
PDE4A P27815 1/20 0.58
ADRA1A P35348 1/20 0.58
KDR P35968 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
NSD2 O96028 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712255 0.90 HSD17B10 (0.71) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL3657327 0.89 HSD17B10 (0.65) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL10787555 0.87 HPGD (0.58) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL2519840 0.86 HPGD (1.00) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL24326 0.86 HPGD (1.00) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL29625250 0.86 HPGD (1.00) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL29107086 0.86 HPGD (0.57) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL21519783 0.85 HPGD (0.96) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL21192457 0.85 HPGD (0.96) HSD17B10HPGDALOX15MAPTKDM4E
Phenyl Salicylate SCHEMBL14151784 0.85 HPGD (0.96) HSD17B10HPGDALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277590-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR FIBERS LANDA LABS (2012) LTD. (IL) 2024-08-22 US disclosed
EP-4387584-A1 IMPROVED COMPOSITIONS AND METHODS FOR STYLING HAIR FIBERS Landa Labs (2012) Ltd. (IL) 2024-06-26 EP disclosed
CN-117858692-A Improved compositions and methods for styling hair fibers 兰达实验室(2012)有限公司 2024-04-09 CN disclosed
WO-2023021455-A1 IMPROVED COMPOSITIONS AND METHODS FOR STYLING HAIR FIBERS LANDA LABS (2012) LTD. (IL) 2023-02-23 WO disclosed
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed
US-4448730-A ANTITUMOR AGENTS RIET BARTHOLOMEUS VAN T 1984-05-15 US disclosed
US-4394389-A ANTITUMOR AGENTS RIET BARTHOLOMEUS VAN T 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277590-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR FIBERS POLR1C, SUCLG1, NACA HSD17B10 2981/4885HPGD 801/4885ALOX15 1069/4885
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 HSD17B10 963/4885HPGD 3545/4885ALOX15 4154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.